HLA B27 and risk of ankylosing spondylitis.

نویسنده

  • A Dixon
چکیده

'Noble, W C, and Naidoo, J, British Journal of Dermatology, 1978, 98, 481. 2 Porthouse, A, et al, Lancet, 1976, 1, 20. 3Ayliffe, G A J, et al, Journal of Clinical Pathology, 1977, 30, 40. 4Lacey, R W, Journal of Medical Microbiology, 1971, 4, 73. 5 Selwyn, S, and Chalmers, D, British J3ournal of Dermatology, 1965, 77, 349. 6 British Medical3Journal, 1978, 1, 1573. 7British Medical3Journal, 1977, 1, 1494. 8 British Medical_Journal, 1977, 1, 337. 9 Tuke, W., Nursing Times, 1975, 71, 21. '° George, R H, in Chemotherapy, vol 3, eds J D Williams and A M Geddes, p 3. New York, Plenum Publishing Company, 1976. "Shepherd, R C, and Kinmonth, J B, British Medical3Journal, 1962, 2, 151. 12 Grant, J C, British Medical3Journal, 1968, 4, 646. 13 Lowbury, E J L, et al, British Medical_Journal, 1976, 1, 493. 14 Babb, J R, et al, Burns, 1977, 3, 65. 15 Gilmore, 0 J A, Annals of the Royal College of Surgeons of England, 1977, 59, 93. 16 Georgiade, N G, and Harris, W A, Plastic and Reconstructive Surgery, 1973, 52, 640. 17 Pollock, A V, and Evans, M, British Journal of Surgery, 1975, 62, 292. 18 Carpenter, C L, et al, Current Therapeutic Research, 1973, 15, 650. 19 Copeman, P W M, and Selwyn, S, British Medical,Journal, 1975, 4, 264.

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منابع مشابه

ASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN

Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.

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Distribution of HLA-B*27 Alleles in Pa-tients with Ankylosing Spondylitis in Iran

Background: HLA-B*27 is strongly associated with ankylosing spondylitis (AS). It represents a family of alleles that differ among ethnic groups. Objective: The aim of this study was to determine the distribution of HLA-B*27 alleles in AS patients and healthy controls in Isfahan (Iran). Methods: Sixty AS patients and 430 healthy blood donors were selected. All subjects were HLA-B*27 positive by ...

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Polymorphism of HLA-B27: 105 subtypes currently known.

HLA-B27 has a high degree of genetic polymorphism, with 105 known subtypes, named HLA-B*27:01 to HLA-B*27:106, encoded by 132 alleles. The most common subtypes associated with ankylosing spondylitis are HLA-B*27:05 (Caucasians), HLA-B*27:04 (Chinese), and HLA-B*27:02 (Mediterranean populations). For Chinese populations, HLA-B*27:04 is associated with a greater ankylosing spondylitis risk than H...

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The HLA system and the arthropathies associated with psoriasis.

Histocompatibility typing was carried out in 74 patients with psoriasis and an inflammatory arthropathy. In 40 patients with peripheral arthropathy characterized by distal interphalangeal joint involvement, 13 (32-5%) were HLA-B27 positive, significantly higher than the control frequency (P = 5-8 X 10 (-6). 26 of the 40 patients did not have ankylosing spondylitis or radiological sacroiliitis a...

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Interaction between HLA-B60 and HLA-B27 as a Better Predictor of Ankylosing Spondylitis in a Taiwanese Population

OBJECTIVE Ankylosing spondylitis (AS) is a form of chronic inflammatory spondyloarthritis (SpA) that causes pain and stiffness in spines or joints. Human leukocyte antigen B27 (HLA-B27) and B60 (HLA-B60) have been reported as major genetic risk factors of AS. In addition, rs13202464, located on major histocompatibility complex (MHC) region, showed high sensitivity (98.7%) and specificity (98.0%...

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Acute anterior uveitis, ankylosing spondylitis, back pain, and HLA-B27.

One hundred and sixty-nine patients with acute anterior uveitis were studied for the presence of HLA-B27 tissue type, radiological evidence of ankylosing spondylitis, and a history of back pain. 60% were male; 45% were HLA-B27+. The male:female ratio in the HLA-B27+ group was the same as in the whole group. 24% had radiological evidence of ankylosing spondylitis, and, of these, 83% were HLA-B27...

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عنوان ژورنال:
  • British medical journal

دوره 2 6142  شماره 

صفحات  -

تاریخ انتشار 1978